2-(4-Fluoro-2-methylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
98%
Reagent
Code: #189840
CAS Number
815631-56-2
blur_circular Chemical Specifications
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Molecular Information
Weight
236.09 g/mol
Formula
C₁₃H₁₈BFO₂
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Registry Numbers
MDL Number
MFCD05863911
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Storage & Handling
Storage
Room temperature, seal, dry
description Product Description
Used as a key intermediate in Suzuki-Miyaura cross-coupling reactions, enabling the formation of carbon-carbon bonds in pharmaceutical and agrochemical synthesis. Its boronate ester group facilitates efficient coupling with aryl or heteroaryl halides under palladium catalysis, making it valuable in the development of complex organic molecules, particularly in drug discovery and materials science. The presence of the fluorine atom enhances binding selectivity and metabolic stability in bioactive compounds, while the methyl group can influence steric and electronic properties of the target molecule. Commonly employed in late-stage functionalization to introduce fluorinated aromatic motifs into larger scaffolds.
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