4-Fluoro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine
95%
Reagent
Code: #188250
CAS Number
1260152-43-9
blur_circular Chemical Specifications
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Molecular Information
Weight
223.05 g/mol
Formula
C₁₁H₁₅BFNO₂
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Registry Numbers
MDL Number
MFCD07367517
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Storage & Handling
Storage
Room temperature, sealed, dry
description Product Description
Widely used in cross-coupling reactions, this compound serves as a key building block in the synthesis of pharmaceuticals and agrochemicals. Its boronate ester group enables efficient Suzuki-Miyaura coupling, allowing the formation of carbon-carbon bonds under mild conditions. It is particularly valuable in the preparation of fluorinated heteroaromatic systems, which are common motifs in drug discovery due to their enhanced metabolic stability and bioavailability. The presence of the fluorine atom also allows for further functionalization or use in radiolabeling applications, especially in PET imaging probes. Its stability and reactivity make it a preferred intermediate in both academic research and industrial-scale synthesis.
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