2-(2-Fluoro-4-(trifluoromethyl)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
98%
Reagent
Code: #188059
CAS Number
1073353-68-0
blur_circular Chemical Specifications
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Molecular Information
Weight
290.06 g/mol
Formula
C₁₃H₁₅BF₄O₂
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Registry Numbers
MDL Number
MFCD08458187
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Physical Properties
Boiling Point
288.1±40.0℃ at 760 mmHg
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Storage & Handling
Density
1.20±0.1 g/cm3
Storage
2-8℃, sealed, dried
description Product Description
Widely used in Suzuki-Miyaura cross-coupling reactions, this compound serves as a key boronic ester reagent for forming carbon-carbon bonds in pharmaceutical and agrochemical synthesis. Its stability and reactivity make it ideal for constructing biaryl structures, commonly found in active pharmaceutical ingredients. It is also employed in the development of organic electronic materials due to its ability to introduce fluorinated aromatic groups, which can enhance electron transport properties and thermal stability. The presence of fluorine and trifluoromethyl groups improves metabolic stability in drug candidates, making this reagent valuable in medicinal chemistry for late-stage functionalization.
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