2-Fluoro-4-methylphenylboronic acid pinacol ester
98%
Reagent
Code: #188051
CAS Number
1165936-03-7
blur_circular Chemical Specifications
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Molecular Information
Weight
254.1055032 g/mol
Formula
C₁₃H₂₀BFO₃
thermostat
Physical Properties
Melting Point
58-60℃
Boiling Point
300.9±35.0℃(Predicted)
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Storage & Handling
Density
1.04±0.1g/ml(Predicted)
Storage
2-8℃, dry, sealed
description Product Description
Used as a key intermediate in Suzuki-Miyaura cross-coupling reactions for the synthesis of complex organic molecules, particularly in pharmaceutical and agrochemical research. Its fluorinated aromatic structure enhances binding selectivity and metabolic stability in drug candidates. Commonly employed in the development of bioactive compounds where fluorine substitution is critical for activity. The pinacol ester group improves stability and handling compared to the free boronic acid, making it more suitable for large-scale and automated synthesis.
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