2-(2-Fluoro-5-nitrophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
98%
Reagent
Code: #187692
CAS Number
425378-68-3
blur_circular Chemical Specifications
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Molecular Information
Weight
267.06 g/mol
Formula
C₁₂H₁₅BFNO₄
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Storage & Handling
Storage
2-8°C
description Product Description
Used as an intermediate in Suzuki-Miyaura cross-coupling reactions, this compound enables the formation of carbon-carbon bonds in the synthesis of complex organic molecules, particularly in pharmaceuticals and agrochemicals. Its boronate ester group facilitates coupling with aryl or heteroaryl halides under palladium catalysis, allowing efficient construction of biaryl structures. The presence of a nitro group and fluorine substituent offers additional reactivity handles for downstream functionalization, making it valuable in medicinal chemistry for building drug-like scaffolds. It is especially useful in the development of fluorinated compounds where enhanced metabolic stability and bioavailability are desired.
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