2-(2-Fluoro-5-nitrophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

98%

Reagent Code: #187692
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CAS Number 425378-68-3

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 267.06 g/mol
Formula C₁₂H₁₅BFNO₄
inventory_2 Storage & Handling
Storage 2-8°C

description Product Description

Used as an intermediate in Suzuki-Miyaura cross-coupling reactions, this compound enables the formation of carbon-carbon bonds in the synthesis of complex organic molecules, particularly in pharmaceuticals and agrochemicals. Its boronate ester group facilitates coupling with aryl or heteroaryl halides under palladium catalysis, allowing efficient construction of biaryl structures. The presence of a nitro group and fluorine substituent offers additional reactivity handles for downstream functionalization, making it valuable in medicinal chemistry for building drug-like scaffolds. It is especially useful in the development of fluorinated compounds where enhanced metabolic stability and bioavailability are desired.

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Size Availability Unit Price Quantity
inventory 250mg
10-20 days ฿148.50
inventory 1g
10-20 days ฿450.00

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