2-Fluoro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine
97%
Reagent
Code: #187636
CAS Number
444120-95-0
blur_circular Chemical Specifications
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Molecular Information
Weight
223.05 g/mol
Formula
C₁₁H₁₅BFNO₂
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Registry Numbers
MDL Number
MFCD03412792
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Physical Properties
Melting Point
29-33°C
Boiling Point
304.2°C
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Storage & Handling
Storage
2-8°C
description Product Description
Used as a key intermediate in Suzuki-Miyaura cross-coupling reactions for the synthesis of pharmaceuticals and agrochemicals. Its boronate ester group enables efficient carbon-carbon bond formation, particularly in the development of fluorinated pyridine derivatives which are common motifs in bioactive molecules. Widely applied in medicinal chemistry for constructing drug candidates targeting CNS disorders, inflammation, and oncology. Also utilized in materials science for creating fluorinated organic semiconductors and liquid crystals due to enhanced electronic properties and stability imparted by the fluorine atom.
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