2-(2-Fluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
97%
Reagent
Code: #187623
CAS Number
876062-39-4
blur_circular Chemical Specifications
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Molecular Information
Weight
222.06 g/mol
Formula
C₁₂H₁₆BFO₂
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Registry Numbers
MDL Number
MFCD05663874
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Physical Properties
Boiling Point
284.6±23.0°C
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Storage & Handling
Storage
2-8°C
description Product Description
Widely used in Suzuki-Miyaura cross-coupling reactions, this compound serves as a key boronic ester reagent for forming carbon-carbon bonds in organic synthesis. It is particularly valuable in pharmaceutical and agrochemical industries for constructing biaryl frameworks, where the fluorophenyl group influences electronic and metabolic properties. Its stability and reactivity profile make it suitable for late-stage functionalization in complex molecule assembly. Commonly employed in medicinal chemistry for drug discovery and development, especially in creating fluorinated analogs with improved bioavailability or target selectivity.
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