3-Fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzaldehyde
97%
Reagent
Code: #186784
CAS Number
1352657-25-0
blur_circular Chemical Specifications
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Molecular Information
Weight
250.07 g/mol
Formula
C₁₃H₁₆BFO₃
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Registry Numbers
MDL Number
MFCD18732921
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Storage & Handling
Storage
2-8°C, Inert Gas
description Product Description
Used as an intermediate in Suzuki-Miyaura cross-coupling reactions for the synthesis of biaryl compounds in pharmaceutical and agrochemical research. Its aldehyde and boronate functional groups allow dual reactivity, enabling sequential transformations to build complex aromatic structures. Commonly employed in the development of active pharmaceutical ingredients (APIs) and functional materials where fluorinated aromatic aldehydes are required. The boronate ester group facilitates palladium-catalyzed coupling, while the aldehyde can be further modified through reduction, condensation, or nucleophilic addition. Valued in medicinal chemistry for introducing fluorinated benzaldehyde motifs with high selectivity.
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