ethyl 2-(5,5-dimethyl-1,3,2-dioxaborinan-2-yl)benzoate
95%
Reagent
Code: #183483
CAS Number
346656-34-6
blur_circular Chemical Specifications
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Molecular Information
Weight
262.1093 g/mol
Formula
C₁₄H₁₉BO₄
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Registry Numbers
MDL Number
MFCD00064090
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Physical Properties
Boiling Point
384.8℃ at 760 mmHg
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Storage & Handling
Storage
2-8℃, dry, sealed
description Product Description
Used as a key reagent in Suzuki-Miyaura cross-coupling reactions, enabling the formation of carbon-carbon bonds in pharmaceutical and agrochemical synthesis. Its boronate ester group facilitates palladium-catalyzed coupling with aryl halides, making it valuable for constructing biaryl frameworks found in active pharmaceutical ingredients. The presence of the ester group allows for further functionalization, such as hydrolysis or reduction, adding versatility in synthetic pathways. Stable and compatible with a range of reaction conditions, it is particularly useful in late-stage functionalization during drug development.
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