2-(3-(Difluoromethyl)-4,5-difluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
98%
Reagent
Code: #180000
CAS Number
2001545-43-1
blur_circular Chemical Specifications
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Molecular Information
Weight
290.06 g/mol
Formula
C₁₃H₁₅BF₄O₂
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Storage & Handling
Storage
Room temperature
description Product Description
Used as a key intermediate in Suzuki-Miyaura cross-coupling reactions, enabling the synthesis of complex organic molecules, particularly in pharmaceutical and agrochemical industries. Its boronate ester group facilitates efficient carbon-carbon bond formation under mild conditions, making it valuable in the development of active pharmaceutical ingredients (APIs) and functional materials. The presence of fluorine atoms enhances reactivity and stability, improving selectivity in coupling processes. Commonly employed in late-stage functionalization to introduce difluoromethyl and fluoroaryl motifs, which are important for tuning metabolic stability and bioavailability in drug candidates.
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