1-(1,3-Dioxolan-2-ylmethyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole
98%
Reagent
Code: #178149
CAS Number
864754-17-6
blur_circular Chemical Specifications
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Molecular Information
Weight
280.13 g/mol
Formula
C₁₃H₂₁BN₂O₄
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Registry Numbers
MDL Number
MFCD08272028
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Physical Properties
Melting Point
174-178 °C
Boiling Point
405.6 °C at 760 mmHg
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Storage & Handling
Storage
Room temperature
description Product Description
Used primarily as a key intermediate in Suzuki-Miyaura cross-coupling reactions, enabling the formation of carbon-carbon bonds in pharmaceutical and agrochemical synthesis. Its pyrazole and boronate functional groups allow for selective and efficient coupling with aryl or heteroaryl halides under palladium catalysis. This makes it valuable in constructing complex molecules, especially in drug discovery and development of bioactive compounds. The dioxolane group can act as a protected aldehyde, offering further synthetic versatility through deprotection to reveal reactive carbonyl functionalities downstream. Its stability and reactivity profile support use in multi-step organic syntheses.
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