2,4-Dimethyl-5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-pyrimidine
95%
Reagent
Code: #176249
CAS Number
1951411-46-3
blur_circular Chemical Specifications
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Molecular Information
Weight
234.10246 g/mol
Formula
C₁₂H₁₉BN₂O₂
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Storage & Handling
Storage
-20°C, sealed, dry
description Product Description
Used primarily in cross-coupling reactions, this compound serves as a key building block in the synthesis of pharmaceuticals and agrochemicals. Its boronate ester group enables efficient Suzuki-Miyaura coupling, allowing the formation of carbon-carbon bonds under mild conditions. It is especially valuable in medicinal chemistry for constructing pyrimidine-based scaffolds found in bioactive molecules. The presence of methyl groups enhances stability and influences reactivity, improving selectivity in complex syntheses. Commonly employed in research and process chemistry for developing kinase inhibitors and other therapeutic agents.
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