2,3-Difluoro-4-methylphenylboronic acid pinacol ester
98%
Reagent
Code: #175612
CAS Number
1116681-99-2
blur_circular Chemical Specifications
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Molecular Information
Weight
272.0959664 g/mol
Formula
C₁₃H₁₉BF₂O₃
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Registry Numbers
MDL Number
MFCD23379473
thermostat
Physical Properties
Boiling Point
305.4±42.0℃ at 760 mmHg
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Storage & Handling
Density
1.10±0.1 g/cm3
Storage
2-8℃
description Product Description
Used in Suzuki-Miyaura cross-coupling reactions to synthesize fluorinated biaryl compounds, which are important in pharmaceutical and agrochemical development. Its boronic ester group provides enhanced stability and handling compared to the corresponding boronic acid, making it suitable for large-scale synthesis. The presence of fluorine atoms improves metabolic stability and lipophilicity in drug candidates. Commonly employed in the preparation of kinase inhibitors and other bioactive molecules where fluorinated aromatic rings are required. Also utilized in materials science for constructing conjugated organic systems with tuned electronic properties.
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