1,3,2-Dioxaborolane,2-(3-fluoro-4-methoxyphenyl)-4,4,5,5-tetramethyl-
98%
Reagent
Code: #175599
CAS Number
754226-34-1
blur_circular Chemical Specifications
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Molecular Information
Weight
252 g/mol
Formula
C₁₃H₁₈BFO₃
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Registry Numbers
MDL Number
MFCD05863912
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Physical Properties
Boiling Point
329.1±32.0℃ at 760 mmHg
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Storage & Handling
Density
1.08±0.1 g/cm3
Storage
Room temperature
description Product Description
Used primarily as an intermediate in the synthesis of pharmaceuticals and agrochemicals, this compound serves as a boronic ester reagent in Suzuki-Miyaura cross-coupling reactions. Its structure enables efficient carbon-carbon bond formation, particularly in the construction of biaryl systems found in active pharmaceutical ingredients. The presence of the fluoro and methoxy substituents enhances reactivity and selectivity in coupling processes, making it valuable in the development of complex organic molecules. It is especially useful in medicinal chemistry for building fluorinated aromatic frameworks, which can improve metabolic stability and bioavailability in drug candidates.
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