5,5-dimethyl-2-[3-(trifluoromethyl)phenyl]-1,3,2-dioxaborinane
98%
Reagent
Code: #175545
CAS Number
635305-32-7
blur_circular Chemical Specifications
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Molecular Information
Weight
258.044 g/mol
Formula
C₁₂H₁₄BF₃O₂
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Storage & Handling
Storage
2-8℃
description Product Description
Used as a boronic ester reagent in Suzuki-Miyaura cross-coupling reactions to form carbon-carbon bonds in pharmaceutical and agrochemical synthesis. Its trifluoromethylphenyl group enhances lipophilicity and metabolic stability in drug candidates. The 5,5-dimethyl-1,3,2-dioxaborinane structure offers improved stability and reactivity compared to simple boronic acids, making it valuable in late-stage functionalization of complex molecules. Commonly employed in the development of bioactive compounds and functional materials requiring fluorinated aromatic motifs.
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