5,5-dimethyl-2-[2-(trifluoromethyl)phenyl]-1,3,2-dioxaborinane
98%
Reagent
Code: #175544
CAS Number
95753-22-3
blur_circular Chemical Specifications
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Molecular Information
Weight
258.044 g/mol
Formula
C₁₂H₁₄BF₃O₂
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Storage & Handling
Storage
2-8℃
description Product Description
Used as a boronic ester reagent in Suzuki-Miyaura cross-coupling reactions, enabling the formation of carbon-carbon bonds in pharmaceutical and agrochemical synthesis. Its steric hindrance from the 5,5-dimethyl groups and electron-deficient aryl group (due to the trifluoromethyl substituent) enhance selectivity and stability during coupling, particularly useful in complex molecule assembly. Commonly employed in late-stage functionalization of bioactive compounds where robust and selective transmetalation is required.
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