3,5-Dimethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1-tosyl-1H-indazole
97%
Reagent
Code: #171330
CAS Number
1421252-90-5
blur_circular Chemical Specifications
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Molecular Information
Weight
426.34 g/mol
Formula
C₂₂H₂₇BN₂O₄S
thermostat
Physical Properties
Boiling Point
594.3±60.0°C
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Storage & Handling
Storage
Room temperature, dry
description Product Description
Used as a key intermediate in Suzuki-Miyaura cross-coupling reactions, enabling the formation of carbon-carbon bonds in pharmaceutical synthesis. Its boronate ester group facilitates coupling with aryl or heteroaryl halides under palladium catalysis, making it valuable in constructing complex indazole-based scaffolds found in bioactive molecules and drug candidates. Commonly applied in the development of kinase inhibitors and other therapeutic agents where precise molecular architecture is critical. Stable and compatible with a range of functional groups, it supports efficient and selective late-stage functionalization in medicinal chemistry research.
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