5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzo[d]isoxazole
98%
Reagent
Code: #168310
CAS Number
837392-66-2
blur_circular Chemical Specifications
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Molecular Information
Weight
245.08 g/mol
Formula
C₁₃H₁₆BNO₃
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Registry Numbers
MDL Number
MFCD09027764
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Physical Properties
Boiling Point
366.1±15.0 °C(Predicted)
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Storage & Handling
Density
1.14±0.1 g/cm3(Predicted)
Storage
-20°C, Sealed, Inert Gas
description Product Description
Used primarily in cross-coupling reactions, this compound serves as a key intermediate in the synthesis of pharmaceuticals and agrochemicals. Its boronate ester group enables efficient Suzuki-Miyaura coupling, allowing the formation of biaryl structures under mild conditions. It is especially valuable in medicinal chemistry for constructing isoxazole-containing drug candidates, which exhibit biological activities such as kinase inhibition and anti-inflammatory effects. The stability and reactivity of the boronate moiety make it suitable for high-throughput screening and parallel synthesis in drug discovery programs.
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