2-Chloro-4-fluoro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine
96%
Reagent
Code: #165908
CAS Number
1256359-04-2
blur_circular Chemical Specifications
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Molecular Information
Weight
257.5 g/mol
Formula
C₁₁H₁₄BClFNO₂
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Registry Numbers
MDL Number
MFCD17926497
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Storage & Handling
Storage
2-8°C, sealed, dry, inert gas
description Product Description
Widely used in Suzuki-Miyaura cross-coupling reactions, this compound serves as a key intermediate in the synthesis of pharmaceuticals and agrochemicals. Its boronate ester group enables efficient carbon-carbon bond formation under mild conditions, making it valuable in drug discovery and development. It is particularly useful for constructing biaryl and heteroaryl frameworks found in active pharmaceutical ingredients. The presence of both chlorine and fluorine allows for selective reactivity, enabling sequential coupling reactions. It is also employed in the preparation of functional materials such as organic semiconductors and ligands for catalysis.
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