2-(3-Chloro-4-ethoxy-5-fluorophenyl)-4, 4, 5, 5-tetramethyl-1, 3, 2-dioxaborolane
95%
Reagent
Code: #164043
CAS Number
1668474-08-5
blur_circular Chemical Specifications
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Molecular Information
Weight
300.56 g/mol
Formula
C₁₄H₁₉BClFO₃
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Registry Numbers
MDL Number
MFCD24368960
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Storage & Handling
Storage
Room temperature, dry
description Product Description
Used primarily as a key intermediate in pharmaceutical synthesis, especially in Suzuki-Miyaura cross-coupling reactions to form carbon-carbon bonds. Its boronate ester group enables efficient coupling with aryl halides, making it valuable in constructing complex aromatic systems found in bioactive molecules. Commonly applied in the development of fluorinated and chlorinated drug candidates, where precise substitution patterns are critical for biological activity. Its ethoxy and fluoro substituents contribute to improved metabolic stability and target binding in medicinal chemistry applications.
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