2-Chloro-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine
98%
Reagent
Code: #163146
CAS Number
652148-92-0
blur_circular Chemical Specifications
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Molecular Information
Weight
239.51 g/mol
Formula
C₁₁H₁₅BClNO₂
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Registry Numbers
MDL Number
MFCD06798259
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Physical Properties
Melting Point
107-110 °C
Boiling Point
338.2 °C at 760 mmHg
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Storage & Handling
Storage
-20°C, sealed, dry
description Product Description
Widely used in cross-coupling reactions, especially in Suzuki-Miyaura coupling, to introduce the 2-chloropyridine moiety into complex organic molecules. This compound serves as a key building block in the synthesis of pharmaceuticals, agrochemicals, and functional materials due to its reactivity with aryl and heteroaryl halides in the presence of palladium catalysts. Its boronate ester group enables efficient carbon-carbon bond formation under mild conditions, making it valuable in medicinal chemistry for constructing biaryl systems. Commonly employed in late-stage functionalization where stability and selectivity are critical.
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