5-Chloro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline
97%
Reagent
Code: #162041
CAS Number
863578-21-6
blur_circular Chemical Specifications
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Molecular Information
Weight
253.53 g/mol
Formula
C₁₂H₁₇BClNO₂
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Registry Numbers
MDL Number
MFCD11617915
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Storage & Handling
Storage
2-8°C, protected from light, stored in inert gas
description Product Description
Used primarily as a key intermediate in Suzuki-Miyaura cross-coupling reactions, this compound enables the formation of carbon-carbon bonds in the synthesis of complex organic molecules. Its boronate ester group readily reacts with aryl or heteroaryl halides in the presence of a palladium catalyst, making it valuable in pharmaceutical and agrochemical research. It is especially useful for constructing biaryl frameworks found in active pharmaceutical ingredients (APIs) and functional materials. The presence of the amine group allows for further derivatization, enhancing its utility in multi-step syntheses and library generation for drug discovery.
format_list_bulleted Product Specification
| Test Parameter | Specification |
|---|---|
| Appearance | Off-white to light brown solid |
| Purity (%) | 96.5-100% |
| Infrared Spectrum | Conforms to Structure |
| NMR | Conforms to Structure |
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