Cyclopropyl(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-5,6-dihydropyridin-1(2H)-yl)methanone
≥95%
science Other reagents with same CAS 1616388-38-5
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description Product Description
Used primarily as a key intermediate in pharmaceutical synthesis, especially in Suzuki-Miyaura cross-coupling reactions to construct biaryl or heteroaryl frameworks. Its boronate ester group enables efficient carbon-carbon bond formation under mild conditions, making it valuable in the development of active pharmaceutical ingredients (APIs). The cyclopropyl carbonyl moiety contributes to metabolic stability and conformational rigidity in drug candidates, often enhancing potency and selectivity. Commonly applied in the preparation of central nervous system agents, kinase inhibitors, and other bioactive molecules where controlled ring strain and electronic properties are critical.
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