4-Chloro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline
96%
Reagent
Code: #161892
CAS Number
1073371-77-3
blur_circular Chemical Specifications
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Molecular Information
Weight
253.53 g/mol
Formula
C₁₂H₁₇BClNO₂
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Registry Numbers
MDL Number
MFCD06795672
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Physical Properties
Boiling Point
371.2±32.0°C at 760 mmHg
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Storage & Handling
Storage
2-8°C, protected from light, stored in inert gas
description Product Description
Used primarily in cross-coupling reactions, this compound serves as a key intermediate in the synthesis of pharmaceuticals and agrochemicals. Its boronate ester group enables Suzuki-Miyaura coupling, allowing efficient formation of carbon-carbon bonds with aryl or heteroaryl halides under palladium catalysis. This makes it valuable in constructing complex aromatic amines found in bioactive molecules. It is also employed in materials science for developing organic semiconductors and functional polymers due to its ability to introduce chloroaniline motifs into conjugated systems. The compound’s stability and reactivity profile make it suitable for late-stage functionalization in drug discovery.
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