4-chloro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzonitrile

98%

Reagent Code: #161745
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CAS Number 863868-30-8

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 263.53 g/mol
thermostat Physical Properties
Boiling Point 364.9±32.0℃ at 760 mmHg
inventory_2 Storage & Handling
Density 1.16±0.1 g/cm3
Storage 2-8℃

description Product Description

Used primarily as a key intermediate in Suzuki-Miyaura cross-coupling reactions, this compound enables the formation of carbon-carbon bonds in the synthesis of complex organic molecules. Its boronate ester group readily reacts with aryl or vinyl halides in the presence of a palladium catalyst, making it valuable in pharmaceutical and agrochemical research for constructing biaryl frameworks. The nitrile and chloro substituents offer additional functional handles for further derivatization, allowing sequential modifications in multi-step syntheses. It is particularly useful in the development of functional materials and active pharmaceutical ingredients where precise molecular architecture is required.

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Size Availability Unit Price Quantity
inventory 250mg
10-20 days ฿2,230.00
inventory 1g
10-20 days ฿6,250.00
inventory 5g
10-20 days ฿22,190.00

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