1-Cyclopropyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole
95%
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Used primarily as a key intermediate in Suzuki-Miyaura cross-coupling reactions, this compound enables the formation of carbon-carbon bonds in the synthesis of complex organic molecules. Its boronate ester group readily reacts with aryl or heteroaryl halides in the presence of a palladium catalyst, making it valuable in pharmaceutical and agrochemical research. It is especially useful for introducing the cyclopropylpyrazole moiety, a structural motif found in bioactive compounds, including kinase inhibitors and anti-inflammatory agents. The stability and reactivity profile of this reagent support efficient, selective transformations under mild conditions, which is advantageous in late-stage functionalization during drug discovery.
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