3-chloro-2-fluoro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine
≥95%
Reagent
Code: #159329
CAS Number
1220219-73-7
blur_circular Chemical Specifications
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Molecular Information
Weight
257.50 g/mol
Formula
C₁₁H₁₄BClFNO₂
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Registry Numbers
MDL Number
MFCD16995268
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Storage & Handling
Storage
2-8°C
description Product Description
Used as a key intermediate in Suzuki-Miyaura cross-coupling reactions for the synthesis of pharmaceuticals and agrochemicals. Its boronate ester group enables efficient carbon-carbon bond formation, particularly in the development of complex pyridine-based structures. Commonly employed in medicinal chemistry to build fluorinated and chlorinated heteroaromatic systems, which are valuable motifs in drug discovery due to their improved metabolic stability and binding affinity. Also utilized in the preparation of active ingredients in crop protection agents and kinase inhibitors.
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