1-Boc-1,4,5,6-tetrahydropyridine-2-boronic Acid Pinacol Ester
≥97%
Reagent
Code: #156199
CAS Number
865245-32-5
blur_circular Chemical Specifications
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Molecular Information
Weight
309.21 g/mol
Formula
C₁₆H₂₈NO₄B
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Registry Numbers
MDL Number
MFCD07776601
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Physical Properties
Boiling Point
355.2±52.0 °C(Predicted)
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Storage & Handling
Storage
-20°C, light-proof, inert gas
description Product Description
Used in Suzuki-Miyaura cross-coupling reactions to introduce a protected tetrahydropyridine moiety into complex molecules. This compound is particularly valuable in the synthesis of pharmaceutical intermediates and bioactive compounds where a nitrogen-containing heterocycle is required. The Boc group provides protection for the nitrogen, enhancing stability and selectivity during coupling, while the pinacol boronic ester offers improved handling and reactivity. Commonly applied in medicinal chemistry for building blocks in drug discovery, especially in the development of kinase inhibitors and central nervous system agents.
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