tert-Butyl(3-methoxy-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)carbamate
98%
Reagent
Code: #155133
CAS Number
262433-29-4
blur_circular Chemical Specifications
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Molecular Information
Weight
349.23 g/mol
Formula
C₁₈H₂₈BNO₅
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Storage & Handling
Storage
Room temperature, seal, dry
description Product Description
Used primarily in organic synthesis as a protected boronic ester intermediate for Suzuki-Miyaura cross-coupling reactions. The tert-butyl carbamate (Boc) group stabilizes the aniline moiety during coupling, allowing selective formation of biaryl structures commonly found in pharmaceuticals and agrochemicals. After coupling, the Boc group can be easily removed under mild acidic conditions to release the free amine for further functionalization. This compound is especially valuable in the synthesis of complex aromatic amines and drug candidates where chemoselectivity and functional group tolerance are critical.
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