tert-Butyl 6-methyl-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole-1-carboxylate
95%
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description Product Description
Used primarily as a key intermediate in palladium-catalyzed cross-coupling reactions, especially in Suzuki-Miyaura coupling, enabling the formation of carbon-carbon bonds in complex organic synthesis. Its indole core protected with a tert-butoxycarbonyl (Boc) group allows selective functionalization at specific positions, making it valuable in pharmaceutical and agrochemical research. The boronate ester moiety facilitates efficient coupling with aryl or heteroaryl halides, enabling the construction of substituted indole derivatives—structures commonly found in bioactive molecules and drug candidates. Its stability and reactivity profile make it suitable for late-stage diversification in medicinal chemistry campaigns.
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