tert-Butyl 4-(4, 4, 5, 5-tetramethyl-1, 3, 2-dioxaborolan-2-yl)-1H-indazole-1-carboxylate
98%
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Widely used in Suzuki-Miyaura cross-coupling reactions, this compound serves as a key intermediate in the synthesis of complex organic molecules, particularly in pharmaceutical and agrochemical research. The presence of the boronate ester group allows for efficient carbon-carbon bond formation under mild conditions, enabling the construction of biaryl and heteroaryl frameworks. Its indazole core is valuable in drug discovery due to its role as a bioisostere for purine bases, contributing to the development of kinase inhibitors and other biologically active compounds. The tert-butyl carbamate (Boc) protecting group ensures stability during synthesis and can be easily removed when needed, making it ideal for multi-step synthetic routes.
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