tert-Butyl (4-fluoro-3-(4, 4, 5, 5-tetramethyl-1, 3, 2-dioxaborolan-2-yl)phenyl)carbamate
98%
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description Product Description
Widely used in Suzuki-Miyaura cross-coupling reactions, this compound serves as a key intermediate in the synthesis of complex organic molecules, particularly in pharmaceutical and agrochemical industries. The presence of the boronate ester group enables efficient carbon-carbon bond formation with aryl or vinyl halides under palladium catalysis. The tert-butyl carbamate (Boc) protecting group stabilizes the amine functionality during reaction sequences and can be easily removed under mild acidic conditions when needed. Its fluorinated aromatic core makes it valuable for constructing fluorinated target compounds, which often exhibit enhanced metabolic stability and bioavailability in drug development. This reagent is especially useful in medicinal chemistry for building blocks involving fluorinated anilines and biaryl structures.
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