tert-Butyl 3-(4, 4, 5, 5-tetramethyl-1, 3, 2-dioxaborolan-2-yl)piperidine-1-carboxylate
98%
Reagent
Code: #151892
CAS Number
1312713-37-3
blur_circular Chemical Specifications
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Molecular Information
Weight
311.22 g/mol
Formula
C₁₆H₃₀BNO₄
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Registry Numbers
MDL Number
MFCD25509459
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Physical Properties
Boiling Point
358.8 °C at 760 mmHg
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Storage & Handling
Storage
2-8°C, sealed, dry
description Product Description
Widely used in organic synthesis, particularly in Suzuki-Miyaura cross-coupling reactions, this compound serves as a key building block for constructing complex molecules in pharmaceutical and agrochemical research. The presence of the boronate ester group allows for efficient carbon-carbon bond formation under mild conditions. Its piperidine core, protected with a tert-butoxycarbonyl (Boc) group, makes it valuable in the synthesis of nitrogen-containing heterocycles and bioactive compounds. Commonly employed in drug discovery, it enables the introduction of piperidine motifs into target molecules, which are prevalent in central nervous system agents, kinase inhibitors, and other therapeutic agents. The stability and reactivity profile of this reagent support its use in parallel synthesis and combinatorial chemistry workflows.
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