tert-Butyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate

97%

Reagent Code: #149479
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CAS Number 480438-74-2

science Other reagents with same CAS 480438-74-2

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 320.19 g/mol
Formula C₁₇H₂₅BO₅
badge Registry Numbers
MDL Number MFCD03427273
thermostat Physical Properties
Melting Point 84 - 88 ℃ - lit.
Boiling Point 412.1 ℃ at 760 mmHg
inventory_2 Storage & Handling
Density 1.08 g/cm3
Storage Room temperature

description Product Description

Widely used in Suzuki-Miyaura cross-coupling reactions, this compound serves as a key building block for constructing biaryl systems in pharmaceutical and agrochemical synthesis. The boronate ester group readily participates in palladium-catalyzed couplings with aryl halides, enabling efficient formation of carbon-carbon bonds. Its tert-butyl ester functionality remains stable under coupling conditions and can be deprotected later to yield carboxylic acid derivatives. This makes it valuable in multi-step synthesis of complex organic molecules, especially in drug discovery and materials science where precise molecular architecture is critical.

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Size Availability Unit Price Quantity
inventory 1g
10-20 days ฿4,210.00
inventory 5g
10-20 days ฿14,680.00

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tert-Butyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate
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Widely used in Suzuki-Miyaura cross-coupling reactions, this compound serves as a key building block for constructing biaryl systems in pharmaceutical and agrochemical synthesis. The boronate ester group readily participates in palladium-catalyzed couplings with aryl halides, enabling efficient formation of carbon-carbon bonds. Its tert-butyl ester functionality remains stable under coupling conditions and can be deprotected later to yield carboxylic acid derivatives. This makes it valuable in multi-step

Widely used in Suzuki-Miyaura cross-coupling reactions, this compound serves as a key building block for constructing biaryl systems in pharmaceutical and agrochemical synthesis. The boronate ester group readily participates in palladium-catalyzed couplings with aryl halides, enabling efficient formation of carbon-carbon bonds. Its tert-butyl ester functionality remains stable under coupling conditions and can be deprotected later to yield carboxylic acid derivatives. This makes it valuable in multi-step synthesis of complex organic molecules, especially in drug discovery and materials science where precise molecular architecture is critical.

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