1,3-Benzodioxole, 2,2-difluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-
95%
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Used primarily as a key intermediate in Suzuki-Miyaura cross-coupling reactions for the synthesis of complex organic molecules, especially in pharmaceutical and agrochemical research. The presence of the boronate ester group allows for efficient carbon-carbon bond formation under mild conditions, enabling the introduction of the difluorinated benzodioxole moiety into target structures. This unit is valued for its metabolic stability and lipophilicity, making it useful in drug design for enhancing bioavailability and improving pharmacokinetic profiles. It is also employed in the development of functional materials, including liquid crystals and organic electronic compounds, due to its rigid aromatic framework and electron-modulating properties.
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