tert-Butyl 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)picolinate
≥95%
Reagent
Code: #148209
CAS Number
1354356-24-3
blur_circular Chemical Specifications
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Molecular Information
Weight
305.18 g/mol
Formula
C₁₆H₂₄BNO₄
thermostat
Physical Properties
Boiling Point
413.0±30.0°C at 760 mmHg
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Storage & Handling
Storage
2-8°C, stored in inert gas
description Product Description
Used in Suzuki-Miyaura cross-coupling reactions as a boronate ester reagent to introduce pyridine-containing fragments into organic molecules. Its main application is in the synthesis of pharmaceuticals and agrochemicals where the picolinate ester group acts as a directing or functional handle. The tert-butyl protecting group enhances stability and solubility during reaction processes, making it suitable for multi-step synthesis. Commonly employed in medicinal chemistry for constructing biaryl systems with nitrogen heterocycles.
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