tert-Butyl 2-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)acetate
97%
Reagent
Code: #145692
CAS Number
1006875-83-7
blur_circular Chemical Specifications
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Molecular Information
Weight
308.18 g/mol
Formula
C₁₅H₂₅BN₂O₄
thermostat
Physical Properties
Boiling Point
407.4±25.0°C
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Storage & Handling
Storage
2-8°C
description Product Description
Widely used in cross-coupling reactions, this compound serves as a key intermediate in the synthesis of pharmaceuticals and agrochemicals. Its boron-containing group enables Suzuki-Miyaura coupling, allowing efficient formation of carbon-carbon bonds. The tert-butyl acetate substituent on the pyrazole nitrogen protects the carboxylic acid functionality, which can be deprotected after coupling to enable further modification of the molecule. This makes it valuable in medicinal chemistry for building complex heterocyclic systems. It is particularly useful in the development of kinase inhibitors and other bioactive molecules where precise molecular architecture is critical.
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