tert-Butyl (2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl) carbonate
98%
Reagent
Code: #142838
CAS Number
480424-71-3
blur_circular Chemical Specifications
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Molecular Information
Weight
320.19 g/mol
Formula
C₁₇H₂₅BO₅
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Registry Numbers
MDL Number
MFCD03453657
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Physical Properties
Melting Point
73-77 °C
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Storage & Handling
Storage
2-8°C, Inert Gas
description Product Description
Used primarily in organic synthesis as a protected boronic ester reagent, this compound enables the formation of biaryl and aryl-carbon bonds through palladium-catalyzed cross-coupling reactions, such as Suzuki-Miyaura coupling. The tert-butyl carbonate group acts as a protecting group, allowing selective deprotection under mild acidic conditions to reveal phenolic functionalities downstream in multistep syntheses. Its stability and reactivity profile make it valuable in pharmaceutical and agrochemical research for constructing complex aromatic architectures. The boronate ester functionality offers improved shelf life and handling compared to boronic acids, enhancing its utility in high-throughput screening and parallel synthesis.
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