tert-Butyl 5-methoxy-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrolo[2,3-b]pyridine-1-carboxylate
≥98%
Reagent
Code: #140996
CAS Number
1073338-94-9
blur_circular Chemical Specifications
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Molecular Information
Weight
374.2391 g/mol
Formula
C₁₉H₂₇BN₂O₅
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Registry Numbers
MDL Number
MFCD12407272
thermostat
Physical Properties
Boiling Point
491.9±55.0 °C(Predicted)
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Storage & Handling
Density
1.14±0.1 g/cm3(Predicted)
Storage
-20°C, Inert Gas
description Product Description
Used as an intermediate in palladium-catalyzed cross-coupling reactions, particularly in the synthesis of biologically active compounds targeting kinase inhibitors and CNS agents. The boronate ester group enables Suzuki-Miyaura coupling, allowing efficient formation of carbon-carbon bonds in pharmaceutical development. Commonly employed in medicinal chemistry for constructing pyrrolopyridine scaffolds, which are found in several drug candidates due to their favorable binding properties and metabolic stability. Its protected nitrogen facilitates selective reactions at other sites, making it valuable in multi-step syntheses of complex molecules.
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