Methyl 2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-5-(trifluoromethyl)benzoate
97%
Reagent
Code: #132911
CAS Number
873846-89-0
blur_circular Chemical Specifications
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Molecular Information
Weight
330.11 g/mol
Formula
C₁₅H₁₈BF₃O₄
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Registry Numbers
MDL Number
MFCD16996393
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Storage & Handling
Storage
2-8°C
description Product Description
Widely used in cross-coupling reactions, especially in Suzuki-Miyaura coupling, to introduce trifluoromethyl-substituted aromatic systems into complex molecules. Its boronate ester group enables efficient carbon-carbon bond formation under mild conditions, making it valuable in pharmaceutical and agrochemical synthesis. The presence of the electron-withdrawing trifluoromethyl group enhances reactivity and influences the pharmacokinetic properties of target compounds. Commonly employed in the preparation of bioactive molecules, including drug candidates where trifluoromethyl motifs improve metabolic stability and membrane permeability. Also utilized in materials science for constructing functional organic materials with tailored electronic properties.
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