2-Fluoro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol
≥95%
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description Product Description
Used as a key intermediate in Suzuki-Miyaura cross-coupling reactions, this fluorinated boronate ester enables the synthesis of complex biaryl and heterobiaryl molecules, particularly in pharmaceutical, agrochemical, and organic electronics research. The boronate ester group facilitates efficient carbon-carbon bond formation under mild conditions, while the fluorine substituent enhances metabolic stability, bioavailability, and target specificity in drug candidates. The phenolic hydroxyl group allows for further functionalization, such as esterification or ether formation, or incorporation into ligands for catalysis. Commonly employed in medicinal chemistry for lead optimization, library synthesis, and development of active pharmaceutical ingredients.
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