2-Fluoro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol

≥95%

Reagent Code: #131985
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CAS Number 1392234-97-7

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 238.06 g/mol
Formula C₁₂H₁₆BFO₃
badge Registry Numbers
MDL Number MFCD16994403
inventory_2 Storage & Handling
Storage 2-8°C, sealed, dry

description Product Description

Used as a key intermediate in Suzuki-Miyaura cross-coupling reactions, this fluorinated boronate ester enables the synthesis of complex biaryl and heterobiaryl molecules, particularly in pharmaceutical, agrochemical, and organic electronics research. The boronate ester group facilitates efficient carbon-carbon bond formation under mild conditions, while the fluorine substituent enhances metabolic stability, bioavailability, and target specificity in drug candidates. The phenolic hydroxyl group allows for further functionalization, such as esterification or ether formation, or incorporation into ligands for catalysis. Commonly employed in medicinal chemistry for lead optimization, library synthesis, and development of active pharmaceutical ingredients.

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Size Availability Unit Price Quantity
inventory 250mg
10-20 days ฿1,850.00
inventory 1g
10-20 days ฿4,830.00
inventory 5g
10-20 days ฿16,610.00

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