Methyl 2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-4-(trifluoromethyl)benzoate
97%
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Widely used in Suzuki-Miyaura cross-coupling reactions, this compound serves as a key building block in the synthesis of complex organic molecules, particularly in pharmaceutical and agrochemical industries. Its boronate ester group enables efficient carbon-carbon bond formation under mild conditions, making it valuable for constructing biaryl systems. The presence of a trifluoromethyl group enhances the lipophilicity and metabolic stability of target molecules, which is advantageous in drug design. Additionally, the ester functionality allows for further chemical modifications, such as hydrolysis or reduction, enabling versatile downstream derivatization. It is especially useful in the development of fluorinated active pharmaceutical ingredients (APIs) where precise structural control is critical.
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