Methyl 2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-4-(trifluoromethyl)benzoate

97%

Reagent Code: #131730
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CAS Number 1146214-86-9

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 330.11 g/mol
Formula C₁₅H₁₈BF₃O₄
badge Registry Numbers
MDL Number MFCD18756934
thermostat Physical Properties
Boiling Point 381.9±42.0 °C(Predicted)
inventory_2 Storage & Handling
Density 1.21±0.1 g/cm3(Predicted)
Storage 2-8°C, Sealed, Inert Gas

description Product Description

Widely used in Suzuki-Miyaura cross-coupling reactions, this compound serves as a key building block in the synthesis of complex organic molecules, particularly in pharmaceutical and agrochemical industries. Its boronate ester group enables efficient carbon-carbon bond formation under mild conditions, making it valuable for constructing biaryl systems. The presence of a trifluoromethyl group enhances the lipophilicity and metabolic stability of target molecules, which is advantageous in drug design. Additionally, the ester functionality allows for further chemical modifications, such as hydrolysis or reduction, enabling versatile downstream derivatization. It is especially useful in the development of fluorinated active pharmaceutical ingredients (APIs) where precise structural control is critical.

shopping_cart Available Sizes & Pricing

Size Availability Unit Price Quantity
inventory 100mg
10-20 days ฿2,100.00
inventory 250mg
10-20 days ฿3,560.00
inventory 1g
10-20 days ฿10,390.00

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