2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-5-(trifluoromethyl)phenol
98%
Reagent
Code: #131608
CAS Number
1638624-76-6
blur_circular Chemical Specifications
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Molecular Information
Weight
288.07 g/mol
Formula
C₁₃H₁₆BF₃O₃
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Registry Numbers
MDL Number
MFCD16994245
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Physical Properties
Boiling Point
331.1±42.0 °C(Predicted)
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Storage & Handling
Density
1.23±0.1 g/cm3(Predicted)
Storage
2-8°C, sealed, dry
description Product Description
Used primarily in organic synthesis as a boronic ester reagent for Suzuki-Miyaura cross-coupling reactions. Its phenolic hydroxyl group allows for further functionalization or coordination in catalytic systems, making it valuable in the development of pharmaceuticals, agrochemicals, and advanced materials. The presence of the electron-withdrawing trifluoromethyl group enhances reactivity and stability in coupling processes, enabling efficient construction of biaryl compounds. It is also employed in the synthesis of fluorinated organic molecules where controlled molecular architecture is required.
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