1-(3,5-Difluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)cyclobutan-1-ol
95%
Reagent
Code: #131541
CAS Number
1395282-06-0
blur_circular Chemical Specifications
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Molecular Information
Weight
310.14 g/mol
Formula
C₁₆H₂₁BF₂O₃
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Registry Numbers
MDL Number
MFCD23380919
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Physical Properties
Boiling Point
394.0±42.0 °C(Predicted)
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Storage & Handling
Density
1.20±0.1 g/cm3(Predicted)
Storage
2-8°C, sealed, dry
description Product Description
Used as a key intermediate in Suzuki-Miyaura cross-coupling reactions for the synthesis of complex organic molecules, particularly in pharmaceutical and agrochemical research. Its boronate ester group enables efficient carbon-carbon bond formation, allowing for the introduction of the difluorophenylcyclobutanol moiety into target compounds. This structural fragment is valuable in drug discovery due to its metabolic stability and three-dimensional architecture, often employed in the development of bioactive molecules with improved potency and selectivity.
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