Methyl 2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-6-(trifluoromethyl)benzoate
≥95%
Reagent
Code: #131392
CAS Number
1146214-79-0
blur_circular Chemical Specifications
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Molecular Information
Weight
330.11 g/mol
Formula
C₁₅H₁₈BF₃O₄
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Registry Numbers
MDL Number
MFCD18756933
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Physical Properties
Boiling Point
387.3±42.0 °C(Predicted)
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Storage & Handling
Density
1.21±0.1 g/cm3(Predicted)
Storage
2-8°C, sealed, dry
description Product Description
Used primarily in cross-coupling reactions, especially Suzuki-Miyaura coupling, to construct biaryl and heterobiaryl systems in pharmaceutical and agrochemical synthesis. The boronate ester group acts as a key coupling partner with aryl halides, enabling efficient formation of carbon-carbon bonds. Its trifluoromethyl and ester functionalities provide sites for further chemical modification, making it valuable in the development of complex organic molecules, particularly in drug discovery and materials science. The presence of the trifluoromethyl group enhances metabolic stability and lipophilicity in bioactive compounds, increasing its utility in medicinal chemistry.
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