3-Fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzamide
97%
Reagent
Code: #131017
CAS Number
957346-54-2
blur_circular Chemical Specifications
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Molecular Information
Weight
265.09 g/mol
Formula
C₁₃H₁₇BFNO₃
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Registry Numbers
MDL Number
MFCD18732743
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Physical Properties
Boiling Point
358.2±37.0 °C(Predicted)
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Storage & Handling
Density
1.17±0.1 g/cm3(Predicted)
Storage
2-8°C, sealed, dry
description Product Description
Used as a key intermediate in Suzuki-Miyaura cross-coupling reactions for the synthesis of biaryl compounds in pharmaceutical and agrochemical research. Its boronate ester group enables efficient carbon-carbon bond formation under mild conditions, making it valuable in drug discovery for building complex aromatic structures. The presence of a fluorine atom enhances binding selectivity and metabolic stability in target molecules. Commonly employed in the development of kinase inhibitors and other bioactive compounds where fluorinated aromatic scaffolds are required.
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