2,2,2-Trifluoro-1-(4-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)piperazin-1-yl)ethanone
98%
Reagent
Code: #130836
CAS Number
1218791-39-9
blur_circular Chemical Specifications
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Molecular Information
Weight
384.2 g/mol
Formula
C₁₈H₂₄BF₃N₂O₃
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Registry Numbers
MDL Number
MFCD12756469
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Storage & Handling
Storage
2-8°C, sealed, dry
description Product Description
Used as a key intermediate in Suzuki-Miyaura cross-coupling reactions for the synthesis of biaryl compounds in pharmaceutical and agrochemical research. Its boronate ester group enables efficient carbon-carbon bond formation under mild conditions. Commonly employed in the development of functional materials and active pharmaceutical ingredients (APIs) where trifluoromethyl ketone and piperazine motifs are required. Offers good stability and reactivity, making it valuable in medicinal chemistry for constructing complex molecules with enhanced metabolic stability and binding affinity.
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