2,2,2-Trifluoro-1-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethanone

97%

Reagent Code: #130754
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CAS Number 1004294-77-2

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 300.08 g/mol
Formula C₁₄H₁₆BF₃O₃
badge Registry Numbers
MDL Number MFCD16628195
thermostat Physical Properties
Boiling Point 343.9±42.0 °C(Predicted)
inventory_2 Storage & Handling
Density 1.20±0.1 g/cm3(Predicted)
Storage 2-8°C, sealed, dry

description Product Description

Used primarily as a key intermediate in Suzuki-Miyaura cross-coupling reactions, this compound enables the formation of carbon-carbon bonds in the synthesis of pharmaceuticals and agrochemicals. The presence of the trifluoromethyl ketone group adds electron-withdrawing character, which can influence reactivity and stability in drug-like molecules. Its boronate ester functionality allows for efficient coupling with aryl halides, making it valuable in medicinal chemistry for constructing biaryl systems found in bioactive molecules. It is also employed in the development of fluorinated analogs of lead compounds to improve metabolic stability and membrane permeability.

shopping_cart Available Sizes & Pricing

Size Availability Unit Price Quantity
inventory 250mg
10-20 days ฿4,640.00
inventory 1g
10-20 days ฿11,860.00
inventory 5g
10-20 days ฿33,280.00

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