2,2,2-Trifluoro-1-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethanone
97%
science Other reagents with same CAS 1004294-77-2
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description Product Description
Used primarily as a key intermediate in Suzuki-Miyaura cross-coupling reactions, this compound enables the formation of carbon-carbon bonds in the synthesis of pharmaceuticals and agrochemicals. The presence of the trifluoromethyl ketone group adds electron-withdrawing character, which can influence reactivity and stability in drug-like molecules. Its boronate ester functionality allows for efficient coupling with aryl halides, making it valuable in medicinal chemistry for constructing biaryl systems found in bioactive molecules. It is also employed in the development of fluorinated analogs of lead compounds to improve metabolic stability and membrane permeability.
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