2-Chloro-5-methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine
≥95%
Reagent
Code: #130551
CAS Number
1309982-62-4
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Molecular Information
Weight
253.53 g/mol
Formula
C₁₂H₁₇BClNO₂
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Registry Numbers
MDL Number
MFCD08063083
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Storage & Handling
Storage
2-8°C, Sealed, Inert Gas
description Product Description
Used as a key intermediate in Suzuki-Miyaura cross-coupling reactions, enabling the formation of carbon-carbon bonds in pharmaceutical and agrochemical synthesis. Its boronate ester group readily reacts with aryl or heteroaryl halides in the presence of a palladium catalyst, making it valuable for constructing complex pyridine-based structures. Commonly applied in the development of active pharmaceutical ingredients (APIs), particularly in drug discovery programs targeting kinase inhibitors and other bioactive molecules. Its stability and reactivity profile make it suitable for high-throughput screening and parallel synthesis in medicinal chemistry.
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