Disodium tiludronate is primarily used in veterinary medicine to treat bone disorders in horses, particularly navicular disease. It works by inhibiting bone resorption through suppression of osteoclast activity, helping to reduce pain and improve mobility in affected animals. In human medicine, it is approved for Paget's disease of bone and has been explored for managing osteoporosis, although its use is less common compared to other bisphosphonates. Additionally, it is used to treat hypercalcemia of malignancy by inhibiting osteoclasts and controlling elevated blood calcium levels. The compound helps stabilize bone density by preventing the breakdown of bone tissue, making it useful in conditions involving bone loss. Its application requires careful dosing and monitoring to ensure efficacy and minimize potential side effects.